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Year : 2010  |  Volume : 3  |  Issue : 3  |  Page : 307
Management of acute ischemic stroke

Department of Medicine, University College of Medical Sciences, Delhi, India

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Date of Web Publication19-Jul-2010

How to cite this article:
Sharma V, Sharma A. Management of acute ischemic stroke. J Emerg Trauma Shock 2010;3:307

How to cite this URL:
Sharma V, Sharma A. Management of acute ischemic stroke. J Emerg Trauma Shock [serial online] 2010 [cited 2022 Aug 16];3:307. Available from:


We read the otherwise brilliant review on emergency care for cerebrovascular accidents. [1] We have few observations regarding the management of acute ischemic stroke.

Recently, the recommendation regarding administration of tissue plasminogen activator in acute ischemic stroke has been modified and has been increased from 3 to 4.5 h on the basis of the findings of the third European Cooperative Acute Stroke Study (ECASS-3). [2] While the review correctly recommends the use of computed tomography as the initial rapid study, it is important to realise the importance of magnetic resonance imaging (MRI) in the diagnosis of acute ischemia as also excluding mimics. MRI has not only become more readily available but is also quicker to perform than before. The ability of diffusion-weighted imaging to identify acute infarction and of fluid-attenuated inversion recovery sequence and gradient echo in detecting hemorrhage argue for a greater role of MRI in acute stroke. Recent recommendations have indicated that MRI can be utilized in the first 3 h if it does not delay administration of thrombolytic therapy. [3] Also, the review does not mention the need to control hyperglycemia in acute ischemic stroke, which may have some benefit in improving the outcome. [4]

   References Top

1.Birenbaum D. Emergency neurological care of strokes and bleeds. J Emerg Trauma Shock 2010;3:52-61.  Back to cited text no. 1  [PUBMED]  Medknow Journal  
2.del Zoppo GJ, Saver JL, Jauch EC, Adams HP Jr; American Heart Association Stroke Council. Expansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator: a science advisory from the American Heart Association/American Stroke Association. Stroke 2009;40:2945-8.  Back to cited text no. 2  [PUBMED]  [FULLTEXT]  
3.Latchaw RE, Alberts MJ, Lev MH, Connors JJ, Harbaugh RE, Higashida RT, et al. Recommendations for imaging of acute ischemic stroke: a scientific statement from the American Heart Association. Stroke 2009;40:3646-78.  Back to cited text no. 3  [PUBMED]  [FULLTEXT]  
4.Adams HP Jr, del Zoppo G, Alberts MJ, Bhatt DL, Brass L, Furlan A, et al. Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: the American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Stroke 2007;38:1655-711.  Back to cited text no. 4  [PUBMED]  [FULLTEXT]  

Correspondence Address:
Vishal Sharma
Department of Medicine, University College of Medical Sciences, Delhi
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0974-2700.66552

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2 Authoręs reply
Birenbaum, D.
Journal of Emergencies, Trauma and Shock. 2010; 3(3): 307


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