Year : 2009 | Volume
: 2 | Issue : 2 | Page : 132--134
Difficult weaning in delayed onset diaphragmatic hernia
Syed Moied Ahmed, Abu Nadeem, Jyotishka Pal, Rahul Gupta, Sunil Chauhan
Department of Anaesthesiology and Critical Care, JN Medical College, Aligarh Muslim University, Aligarh, India
Syed Moied Ahmed
Department of Anaesthesiology and Critical Care, JN Medical College, Aligarh Muslim University, Aligarh
Diaphragmatic injuries are relatively rare and result from either blunt or penetrating trauma. Regardless of the mechanism, diagnosis is often missed and high index of suspicion is vital. The clinical signs associated with a diaphragmatic hernia can range from no outward signs to immediately life-threatening respiratory compromise. Establishing the clinical diagnosis of diaphragmatic injuries (DI) can be challenging as it is often clinically occult. Accurate diagnosis is critical since missed DI may result in grave sequelae due to herniation and strangulation of displaced intra-abdominal organs. We present a case of polytrauma with rib fracture and delayed appearance of diaphragmatic hernia manifesting as difficult weaning from ventilatory support.
|How to cite this article:|
Ahmed SM, Nadeem A, Pal J, Gupta R, Chauhan S. Difficult weaning in delayed onset diaphragmatic hernia.J Emerg Trauma Shock 2009;2:132-134
|How to cite this URL:|
Ahmed SM, Nadeem A, Pal J, Gupta R, Chauhan S. Difficult weaning in delayed onset diaphragmatic hernia. J Emerg Trauma Shock [serial online] 2009 [cited 2020 May 25 ];2:132-134
Available from: http://www.onlinejets.org/text.asp?2009/2/2/132/50750
The diaphragm is the major muscle of respiration. Spontaneous breathing relies primarily on diaphragmatic excursion to produce negative intrathoracic pressure. Whenever diaphragmatic function decreases, concomitant respiratory dysfunction ensues. Blunt and penetrating injury to the diaphragm is one of the commonest causes of acquired diaphragmatic hernias. Delay in detecting and repairing diaphragmatic injury increases both morbidity and mortality.
A 46-year-old male presented to the casualty with severe respiratory distress associated with chest pain following an alleged history of fall from height. The patient was provisionally diagnosed as a case of blunt trauma chest with bilateral hemothorax with right-sided fracture clavicle. An urgent X-ray chest was advised. Bilateral ICTD were inserted, which resulted in drainage of approximately 600 ml bloody fluid from each ICTD. With the patient developing hypotension, tachypnoea (> 36 breaths/min) and a deteriorating Glasgow Coma Scale (GCS), the patient was intubated and shifted to ICU.
The patient was sedated and ventilatory support was initiated with volume assist control mode initial settings being tidal volume (V T ) of 8 ml/kg, respiratory rate(RR) of 14, inspiratory flow rate (IFR) of 60 L/min, positive end expiratory pressure (PEEP) of 8 cm of H 2 O and FiO 2 of 1. X-ray chest confirmed fracture of right clavicle and right-sided 3 rd , 4 th and 5th ribs. Both the costophrenic angles were obliterated with the bilateral ICTD drain in situ. Fluids and vasoactive agents were administered so as to obtain central venous pressure (CVP) of > 12 cm H 2 O and maintain a mean arterial pressure (MAP) of >65 mmHg. In accordance with arterial blood gas (ABG) analysis after a period of 6 h, which showed a PaO 2 of 200 mmHg, PaCO 2 of 42 mmHg, pH of 7.37 and HCO 3 of 21.3 mEq/L, over the next 18 h, the FiO 2 was gradually reduced to 0.5 and the PEEP was increased to 10 cm H 2 O as the MAP increased to 75 mmHg. Within 48 h of ICU admission, the vasoactive support was gradually tapered off and enteral feeding was initiated. Over the next 48 h (4th ICU day), the requirement of PEEP was reduced to 5 cm H 2 O, minute ventilation (V E ) was reduced to 2 /FiO 2 ratio of > 350. As there was no fresh drainage and the X-ray chest showed fully expanded lungs, both the ICTD were removed. Synchronized intermittent mode (SIMV) was initiated with a back up rate of 12, V T of 450 ml, PS of 10 cm H 2 O and a PEEP of 5 cm H 2 O. On the 6 th ICU day, the patient developed ventilator-associated pneumonia (VAP).
Over the next 2 days (9th ICU day), he remained haemodynamically stable but his ventilatory requirement increased (FiO2 = 0.6, RR = 14, PS = 12) so as to maintain a PaO 2 /FiO 2 ratio of > 300. Because of the anticipated prolonged mechanical ventilation, a percutaneous tracheostomy (PCT) was planned. By the 15th day, as the VAP resolved, it was decided to wean the patient from the ventilator. Over the next 24 h (16th day), the PEEP was reduced to 6, PS was reduced to 8 cm H 2 O and the FiO 2 was maintained at 0.4. The patient was generating a V T of > 400 ml with a PS of 8 cm H 2 O and the spontaneous RR was ranging between 8 and 14/min. With these ventilatory settings, the patient was maintaining a rapid shallow breathing index (RSBI) of 2 O, PEEP of 4 cm H 2 O) on the 17th day and was allowed to remain in the same settings for the next 24 h during which no signs of exhaustion or distress were manifested. His RR ranged between 15 and 19/min, generating a V T of > 450 ml. Considering the past 24-h ventilatory record and the morning ABG, the patient was detached from the ventilator and O 2 was administered @ 3L/min through Ayres T piece connected to the tracheostomy tube. Within 30 min of detachment from the ventilatory support, the patient became exhausted, dyspneic with RR of > 28/min and a SpO 2 of 2 O and gradually increase the duration of trial from 30 min to the maximum time tolerated. The patient remained comfortable with the ventilatory support but deteriorated when detached from the ventilator. Despite 24 h of exercise with that protocol, the ventilatory support could not be reduced. A thorough clinical examination and investigation was done to rule out any lung pathology. On auscultation, air entry was decreased over the left lower chest. X-ray revealed opaque shadow along with the appearance of the distal end of the nasogastric tube over the left lower chest. The presence of the nasogastric tube was confirmed with the presence of gurgling sound on auscultation after administration of air through the nasogastric tube. CTVS Surgeon was referred who diagnosed the case as delayed onset diaphragmatic hernia following blunt trauma chest. The patient was planned for hernia repair by a left thoracotomy approach. Peroperative findings were left pleural space in lower part filled with distended stomach (fundus and part of body) and part of spleen. A single rent of size 30 cm 2 was present in the left dome of diaphragm, which was repaired.
Postoperatively, the patient was electively ventilated for 24 h and gradually weaned and finally detached from the ventilator after 48 h under the cover of O 2 supplementation through Ayre's T piece @ 3 L/min. The patient fared well after removal from the ventilatory support with occasional O 2 supplementation. The patient was decannulated after performing cuff leak test of the tracheostomy tube on the 26th ICU day. He was observed in the ICU for the next 24 h and was shifted to the surgical floor without any further complication.
Diaphragmatic injuries are relatively rare and result from either blunt or penetrating trauma. These injuries were described first by Sennertus in 1541. Riolfi performed the first successful repair in 1886. Not until 1951, when Carter et al. , published the first case series, was this injury well understood and delineated.  Diaphragmatic hernias can be divided into two categories: congenital defects and acquired defects.
Approximately 0.8%-1.6% of patients with blunt trauma show a rupture in the diaphragm.  The male-to-female ratio is 4:1, with most presenting in the third decade of life. Blunt trauma accounts for 75% of ruptures, and penetrating trauma accounts for the rest. Approximately 69% of hernias are left-sided, 24% are right-sided, and 15% are bilateral. , Children have equal rates of rupture per side, likely due to laxity of liver attachments. 
Patients with delayed diaphragmatic herniation frequently present months to years after the initial injury with manifestations of visceral incarceration, obstruction, ischemia from strangulation, or perforation. In our case, it was the difficulty in weaning off mechanical ventilatory support that subsequently led to a suspicion and diagnosis of diaphragmatic herniation.
Symbas et al. , observed a delay in diagnosis in 8% of cases of diaphragmatic injury from 18 h to 15 years after injury.  Chest radiography is the standard in the advanced trauma life support (ATLS) protocol for a trauma workup. Approximately 23-73% of traumatic diaphragmatic ruptures will be detected by initial chest radiograph, with an additional 25% found with subsequent films. Chest radiograph is most sensitive investigation for detecting left-sided hernias. Chest radiographic findings that indicate traumatic rupture include the following: 
Abdominal contents in the thorax, with or without signs of focal constriction ("collar sign")Nasogastric tube seen in the thorax, Elevated hemidiaphragm (>4 cm higher on left vs right) andDistortion of diaphragmatic margin.
Conventional CT scan has been reported to have a sensitivity of 14%-82%, with a specificity of 87%. Helical CT increased sensitivity 71-100%, with higher sensitivity for left vs right. CT findings indicating rupture include the following:
Direct visualization of injurySegmental diaphragm non-visualization Intrathoracic herniation of viscera Collar sign"Peridiaphragmatic active contrast extravasation. 
Ultrasonography (focused assessment with sonography for trauma [FAST] scan) has been reported to detect diaphragmatic hernias.  During the visualization of each upper quadrant, the movement of the diaphragm was noted to be decreased in patients with diaphragmatic hernias. This technique is limited in patients who are on mechanical ventilation because of the positive pressure of the thoracic cavity. th
Surgery is mainstay in the treatment of diaphragmatic rupture.  Operative repair is technically more difficult if the surgery is delayed. The difference is based on the degree of adhesion present in the thoracic cavity and the state of the herniated organs. After reduction of the abdominal contents, the diaphragm can usually be repaired simply with monofilament nonabsorbable suture.
The pressure difference between the abdominal peritoneum and pleural cavities is 7-20 cm of water in quite breathing but could be as high as 100 cm of water in forced respiration.  When diaphragm ruptures, this pressure difference causes the abdominal viscera to herniate through the defect into the chest cavity. 
In this case, while the patient was on mechanical ventilation, the intrathoracic pressure was constantly higher than the intra abdominal pressure due to the effect of positive pressure ventilation. However, as long as the patient was on CPAP/PSV, the patient did not manifest any symptoms of respiratory embarrassment. It was only when the patient was detached from the ventilatory support that the effects of spontaneous respiratory efforts created the negative intrathoracic pressure that led to the herniation of the intra abdominal contents through the occult diaphragmatic defect in accordance to the pressure gradient between the abdominal and thoracic cavities.
Diaphragmatic hernia can often be missed. A correct diagnosis remains difficult and is usually made late. Accurate diagnosis is critical however as a missed DI may result in grave sequelae due to herniation and strangulation of displaced intra-abdominal organs. Blunt diaphragmatic rupture (DR) is a rare condition usually masked by multiple associated injuries, which are the main cause of morbidity and mortality. Physicians should consider the diagnosis in patients who have a history of blunt trauma to the chest or abdomen and develop gastrointestinal or respiratory symptoms. The chest x-ray, especially when performed after insertion of a nasogastric tube, is a useful screening tool.  Single or serial plain chest radiographs with a high index of suspicion are diagnostic in most cases. Respiratory distress should be treated with intubation as intercostal drainage (ICD) may not improve the situation and is associated with a high risk of iatrogenic injuries. Even difficulty in weaning off ventilatory support can serve as a clue to the underlying occult defect. Surgical repair is mandatory, and laparotomy should be the preferred approach in unstable patients. To avoid missed injury thorough inspection of both hemidiaphragms should be done routinely on every trauma patient undergoing laparotomy.
|1||Welsford M. Diaphragmatic Injuries. Med J 2001;2:72-6.|
|2||Shah R, Sabanathan S, Mearns AJ, Choudhury AK. Traumatic rupture of the diaphragm. Ann Thorac Surg 1995;60:1444-9.|
|3||Kuhlman JE, Pozniak MA, Collins J, Knisely BL. Radiographic and CT findings of blunt chest trauma: Aortic injuries and looking beyond them. Radiographics 1998;18:1085-106.|
|4||Feliciano DV, Cruse PA, Mattox KL, Bitondo CG, Burch JM, Noon GP, et al . Delayed diagnosis of injuries to the diaphragm after penetrating wounds. J Trauma 1988;28:1135-44. |
|5||Sliker C. Imaging of diaphragm injuries. Radiol Clin North Am 2006;44:199-211.|
|6||Symbas PN, Vlasis SE, Hatcher C Jr. Blunt and penetrating diaphragmatic injuries with or without herniation of organs into the chest. Ann Thorac Surg 1986;42:158-62.|
|7||Blaivas M, Brannam L, Hawkins M, Lyon M, Sriram K. Bedside emergency ultrasonographic diagnosis of diaphragmatic rupture in blunt abdominal trauma. Am J Emerg Med 2004;22:601-4.|
|8||Dhar S, Bhasin SK, Langer JG. Diaphragmatic hernia presenting as empyema thorax. JK Sci 2005;7:1. |
|9||Chaudhary IA, Samiullah, Masood R, Muftee M, Jilani R. Traumatic rupture of diaphragm: Not an easy diagnosis. J Pak Med Assoc Rawalpindi Islamabad2007;32:1. |
|10||Goh BK, Wong AS, Tay KH, Hoe MN. Delayed presentation of a patient with a ruptured diaphragm complicated by gastric incarceration and perforation after apparently minor blunt trauma. Can J Emerg Med 2004;6:277-80.|