Journal of Emergencies, Trauma, and Shock
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CASE REPORT
Year : 2015  |  Volume : 8  |  Issue : 1  |  Page : 58-60

Continuous intravenous flumazenil infusion in a patient with chlordiazepoxide toxicity and hepatic encephalopathy


1 Department of Internal Medicine, Saint Michael's Medical Center, Newark, New Jersey, USA
2 Department of Pulmonary, Saint Michael's Medical Center, Newark, New Jersey, USA
3 Department of Hematology/Oncology, Saint Michael's Medical Center, Newark, New Jersey, USA

Correspondence Address:
Hamid Shaaban
Department of Hematology/Oncology, Saint Michael's Medical Center, Newark, New Jersey
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-2700.145422

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Flumazenil, a benzodiazepine receptor antagonist, is the drug of choice for the diagnosis and treatment of benzodiazepine overdose. We are presenting a patient with chronic alcoholism and alcoholic liver disease, who came with alcohol withdrawal symptoms and treated chlordiazepoxide. Subsequently he developed a prolonged change in mental status that required treatment for benzodiazepine overdose and hepatic encephalopathy with flumazenil infusion for 28 days.


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