Journal of Emergencies, Trauma, and Shock
Home About us Editors Ahead of Print Current Issue Archives Search Instructions Subscribe Advertise Login 
Users online:1501   Print this pageEmail this pageSmall font sizeDefault font sizeIncrease font size   
CASE REPORT
Year : 2015  |  Volume : 8  |  Issue : 1  |  Page : 52-54

Marchiafava-Bignami disease in a trauma patient


1 Department of Surgery, Lincoln Medical and Mental Health Center, Bronx, New York, USA
2 Department of Radiology, Lincoln Medical and Mental Health Center, Bronx, New York, USA
3 Department of Medicine, Lincoln Medical and Mental Health Center, Bronx, New York, USA

Correspondence Address:
Juaquito M Jorge
Department of Surgery, Lincoln Medical and Mental Health Center, Bronx, New York
USA
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-2700.150399

Rights and Permissions

Marchiafava-Bignami disease (MBD) is a rare pathological condition affecting the corpus callosum (CC), characterized by progressive demyelination and necrosis. While usually found in patients with chronic alcoholism, it has rarely been characterized in non-alcoholics. We describe a trauma patient with an unknown mechanism of injury, who was found to have MBD after remaining comatose for a prolonged period of time. Magnetic resonance imaging (MRI) demonstrated restricted diffusion involving the genu, body, and splenium of the CC. The patient eventually awoke but was non-communicative and uncomprehending prior to discharge to a nursing facility. We reviewed the literature and report here the first case of MBD encountered in a trauma patient. In conclusion, MBD is an extremely rare condition in non-alcoholic patients, and the use of MRI is crucial for its identification.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2554    
    Printed70    
    Emailed0    
    PDF Downloaded14    
    Comments [Add]    

Recommend this journal