Journal of Emergencies, Trauma, and Shock
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SYMPOSIUM
Year : 2011  |  Volume : 4  |  Issue : 2  |  Page : 233-243

Clinical pathology of the shock syndromes


Trauma Directorate, Chris Hani Baragwanath Hospital, Johannesburg, South Africa

Correspondence Address:
Fabrizio Giuseppe Bonanno
Trauma Directorate, Chris Hani Baragwanath Hospital, Johannesburg
South Africa
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-2700.82211

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The clinical aspects of shock syndromes are described from their inception as compensated physiology to a stage of decompensation. The clinical significance of hypotension, fluid-responsive and non fluid-responsive hypotension, is discussed. Untimely or inadequate treatment leads to persistent subclinical shock despite adjustments of the macrohemodynamic variables, which evolves in a second hit of physiological deterioration if not aggressively managed. Irreversible shock ensues as consequence of direct hit or as result of inadequate or delayed treatment and is characterized by drug-resistant hypotension.


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