Journal of Emergencies, Trauma, and Shock
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CASE REPORT
Year : 2008  |  Volume : 1  |  Issue : 2  |  Page : 119-122

Epstein-Barr virus-associated hemophagocytic syndrome mimicking severe sepsis


Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Thomas Jefferson University, Philadelphia, USA

Correspondence Address:
Paul E Marik
Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Thomas Jefferson University, Philadelphia
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-2700.43198

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Severe sepsis is amongst the most common reasons for admission to the intensive care unit (ICU) throughout the world and is a common cause of death. The diagnosis of sepsis is usually straightforward, being based on a constellation of clinical and laboratory features. Noninfectious disorders, including pancreatitis, drug reactions, and autoimmune disorders, may cause a systemic inflammatory response that mimics sepsis. We present the case of a 32-year-old male with Epstein-Barr virus-associated hemophagocytic syndrome who presented to the ICU with features of severe sepsis which progressed to multisystem organ failure and death despite aggressive supportive measures.


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